In this episode of the Lifespan podcast, Dr. David Sinclair and co-host Matthew LaPlante dissect the topic of brain aging. The information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. In doing so, I hope to help explain the science in an easy-to-understand manner and I hope to help all our listeners in their journey to be healthier at any stage of life. (0:00:00) Introducing Ep. Never getting the chance to back in the I DID THAT glow of accomplishment and tell , Critical Drinker is a movie critic, an analyst of modern entertainment media and a YouTuber. * Levels - https://levels.link/sinclair Special thanks to our research assistants, Adiv Johnson & Sarah Ryan. In 2022 Ashley put together an international team to investigate the mysterious origins of a 400 year old light phenomenon in rural Colombia. He's the co-host of the Lifespan Podcast. 2: What to Eat and When to Eat for Longevity (00:56:50) The Future Looks Bright Yeah, weve all been there on some level. We are in a new age of sexlessness. Interviews in Health/Life Sciences/BioTech Entrepreneurship, AI, WEB3 and Policy | Get in touch: pod@musty.io, The Knowledge Project Podcast is a rare opportunity to listen to the best in the world on every topic. Before we hear from Professor Ampim, Financial Expert JB Bryan will provide tips on what to do if you unexpectedly , Dr Stephanie Eltz is a Trauma Surgeon and CEO and Co-founder of Doctify, which is basically Yelp/Trustpilot for Doctors. (00:02:54) Estrogen, Progesterone, and Menopause He is a professor in the Department of Genetics and a co-founder of several biotechnology companies. (00:25:05) Exosome Therapy (01:04:56) Thanking the Podcast Team and Wrapping Up Season One In doing so, they discuss organisms that have extreme longevity, the genes that control aging (mTOR, AMPK,. Enjoy listening and please leave a rating, giving us feedback to make this podcast better! In this weeks episode of the Lifespan podcast, Dr. David Sinclair and co-host Matthew LaPlante cover potential anti-aging interventions that are on the cutting edge. (00:50:33) Episode Summary & Key Takeaways - Why Do We Age? Dr. David Sinclair Social: If you don't like what Hollywood's execs tell you to like? Episode 2: Poverty, inequa What causes aging? . NMN, NR, Resveratrol, Metformin & Other Longevity Molecules | Episode 4. (00:37:59) Stem Cell Aging and Cord Blood Banking They share the latest. * Athletic Greens - https://athleticgreens.com/sinclair David and Matthew additionally highlight the latest evidence behind hyperbaric oxygen therapy, cold therapy, and heat therapy. For the full show notes, including the peer-reviewed studies, visit the Lifespan podcast website. Biotracking, Age Reversal & Other Advanced Health Technologies, Medical Interventions (TRT, HGH, Stem Cells, etc.) The societal effects of therapies that successfully extend healthspan and/or lifespan are also considered. They talk about why superficial aging occurs and how external signs of aging are often a reflection of biological age. Learn more at fs.blog/podcast, A podcast network for creators discussing UFOs, the esoteric, spirituality & related phenomena. What about work, wealth, purpose, service, or something else? Sirtuins. They use AI to unlock all the value out of clinical records and produce real world evidence. Matthew LaPlante's Social: Timestamps: (01:06:11) Targeting Aging Upstream He is an expert and pioneer in the field of aging. Change progress. Special thanks to our research assistants, Adiv Johnson & Sarah Ryan. These are the questions and topics we explore every week in conversation with leading voices from health, science, art, industry, mindset, and culture, like Bren Brown, Matthew McConaughey, Mel Robbins, Alex, Elle, Adam Grant, Elizabeth Gilbert, Yung Pueblo, Maya Shankar, Mitch Al Health Theory is a twice weekly interview show, hosted by Quest Nutrition co-founder, Tom Bilyeu. (00:13:56) Peptide Supplementation and Regenerative Signaling The Science of Looking Younger, Longer | Episode 6. Expect to learn why ther, Last Thursday, scientists at Columbia University published a new study finding that cutting down on calories could lead to longer lives. Interviews with health entrepreneurs and leaders having impact at scale. No credit card needed. Its called Awe: The New Science of Everyday Wonder and How It Can, Dr. Axel Montagne is a chancellor's fellow and group leader at the UK Dementia Research Institute at the University of Edinburgh Centre for Clinical Brain Sciences. Hear about the latest developments in aging research, lifestyle practices for longevity, exercise and nutrition science, and more. In this episode of Lifespan, David Sinclair & Matthew LaPlante discuss how to slow, stop, and even reverse aging processes we can see on. (00:07:01) Sponsors Each week Ill be featuring inspirational stories and pr, Each afternoon, kids walk through my neighborhood, on their way home from school, and almost all of them are walking alone, staring down at their phones. David Sinclair Podcast He serves as the host of Lifespan on Scicomm Media. (00:21:55) mTOR & Rapamycin Given the abundance of data available, a special focus is placed on the NAD precursors nicotinamide riboside and nicotinamide mononucleotide. We apologize for the confusion. (00:30:57) Sirtuin Proteins as Epigenetic Regulators of Aging Please note that Lifespan with Dr. David Sinclair is distinct from Dr. Sinclair's teaching and research roles at Harvard Medical School. (00:57:59) Aging is a Medical Condition (00:10:45) Aging is a Controllable Process that can be Slowed & Reversed (01:02:43) Dr. Sinclairs Protocol for Longevity Molecules Health stuff a techbro/sis would find interesting. Getting us started Baltimore activist Lynn Pinder & Pastor Yerby discuss their Educational Initiative to benefi, When was the last time you felt awe? (00:56:11) Longer Life, Population Size, and Economics He will also supply the remedy for the addiction. They share the latest experimental and clinical data for NAD boosters, resveratrol, fisetin, quercetin, rapamycin, spermidine, metformin, and berberine. (01:07:04) Adversity Mimetics Produce Endorphins For the full show notes, including the peer-reviewed studies, visit the Lifespan podcast website. Of course you don't need to make your own yogurt, a store bought version will work adequately. (01:00:18) Skillbatical (0:54:16) Xenohormesis (00:39:14) Metformin (00:48:01) Wrap-up & Takeaways They talk about why superficial aging occurs and how external signs of aging are often a reflection of biological age. Hes also the , Historian & Researcher Professor Manu Ampim interprets Carter G Woodson's call for what is now Black History Month. How to Turn Anxiety Into a Superpower | Dr. Wendy Suzuki, Griot Baba Lumumba, Dr. Arthur Burnett & Dr. Segun Adebayo l The Carl Nelson Show, #113 Mental Models for Health Entrepreneurship Dr Ignacio Medrano (CEO Savana), A. Peter Bailey, Simeon Booker Muhammad & Senghor Baye l The Carl Nelson Show, #338 The Secrets To Living Your Longest, Healthiest Life with Dr Mark Hyman, #159 Dr. Anna Lembke: Between Pleasure and Pain, Dr. Clarence Lusane, Jovani Patterson & Sinclair Skinner l The Carl Nelson Show, #592 - Richard Shotton - 8 Fascinating Psychological Biases, How to Finish What Matters & Get More Free Time | Spotlight Convo. (00:31:56) A Primer on Stem Cells and Yamanaka Factors * Athletic Greens - https://athleticgreens.com/sinclair The Lifespan with Dr. David Sinclair podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.Special thanks to our research assistants, Adiv Johnson & Sarah Ryan. Welcome to Lifespan with Dr. David Sinclair. Restricting calories "works". Our Patreon page: https://www.patreon.com/davidsinclair Timestamps: Over the last 589 episodes, 1000+ hours and nearly 2000 days of working away on this project I've learned a lot, and today I'm going through some of the most important lessons and, What if you were, unknowingly being controlled by unresolved pain from your past, even minor, or momentary experiences, ones that took root and, from that moment on, without you having any idea, limited everything from your relationships to your health, work, wealth, and life? davidasinclair 4 yr. ago Some guy, that's an excellent question. (00:00:00) Kicking Off Episode Five: Interventions on the Cutting Edge And, just kind of walk away, leaving something that couldve been amazing unfinished? (00:00:00) Introducing Episode Seven: Aging of the Brain Please note that Lifespan with Dr. David Sinclair is distinct from Dr. Sinclair's teaching and research roles at Harvard Medical School. (00:02:39) Expressing Gratitude to the Sponsors Journalist A. Peter Bailey, who was at the Audubon Ballroom the evening Malcolm was killed will be in our classroom. 5 years ago on February 12th 2018 I launched this podcast with a conversation in my old company's office in the North East of England. (00:09:51) Thanking the Sponsors In this weeks episode, Dr. David Sinclair and co-host Matthew LaPlante zero in on drugs and supplements that have been reported to combat aspects of aging. Hear about the latest developments in aging research, lifestyle practices for longevity, exercise and nutrition science, and more. Join Dr. David Sinclair, Ph.D. in Lifespan, a popular health podcast that brings the cutting edge of aging and longevity science straight to you. . * Athletic Greens - https://athleticgreens.com/sinclair The expert technical and management leadership David continued to display resulted in an extremely high degree of . Guests: Labours Jon Cruddas MP; human rights activist Peter Tatchell; ConservativeHome editor Jonathan Isaby, psephologist Professor John Curtice; Dr Madsen Pirie, Director of the free-market Adam Smith Institute; LibDem Voice editor Stephen Tall; David Babbs of campaign organisation 38 Degrees, and the New Statesmans Laurie Penny. Humans have the capacity for incredible benevolence and kindness, but also are able to be execute other members of our species with a , Futuristic Researcher Sadiki Bakari takes over our classroom to update us on the latest A. I Artificial Intelligence developments. David Sinclair, Ph.D. on Extending Human Lifespan & the Science Behind Aging - The Rich Roll Podcast David Sinclair, Ph.D. - The Joe Rogan Experience #1349 Dr. David Sinclair on The Theory of Aging, NAD+ Boosters (NR and NMN), Sirtuins, and More - FoundMyFitness with Dr. Rhonda Patrick (00:21:47) Genes that Regulate Aging: mTOR, AMPK, Sirtuins The information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. * Facebook The information provided in this show is not medical advice, nor should it be taken or applied as a replacement for med Sunday morning sermons from Clemson Presbyterian Church. Packed with inspiring stories of resilience, cutting-edge wellbeing revelations, and how each would make the world a happier place if made global dictator for the day. We apologize for the confusion.Thank you to our sponsors: Athletic Greens - https://athleticgreens.com/sinclair InsideTracker - https://insidetracker.com/sinclair Levels - https://levels.link/sinclairOur Patreon page: https://www.patreon.com/davidsinclairLifespan book: https://amzn.to/3sUqurTDr. Thank you to our sponsors: Loading. Join Dr. David Sinclair, Ph.D. in Lifespan, a popular health podcast that brings the cutting edge of aging and longevity science straight to you. He takes it for a cardiovascular condition that is common in his family. About Jobs For the Record. They talk about why superficial aging. In this episode of the Huberman Lab Podcast, learn all about breathing - the biology of respiration, nose versus mouth breathing, benefits of breath for mood, leveraging breath for improved health outcomes, types of breathing, and much more. Dr. David Sinclair is a professor of genetics and co-director of Harvard Medical School's Paul F. Glenn Center for Biology of Aging Research. Apart from supplements, he claims to limit animal protein intake and get most of the protein from plants and vegetables. Early childhood 9:21 Are patient reviews good measures of a doctor? (0:38:44) Intermittent Fasting with Adequate Nutrition (IFAN) * Twitter A law profe, Alex DatePsych is a Neuroscience and Behavioural Science researcher whose work focuses on attractiveness and dating. Our Patreon page: https://www.patreon.com/davidsinclair For the full show notes, including the peer-reviewed studies, visit the Lifespan podcast website. (00:43:37) Cellular Reprogramming In this episode, Dr. David Sinclair and co-host Matthew LaPlante discuss how frequently we should eat, what food we should avoid, and what food we should pursue. Join Dr. David Sinclair, Ph.D. in Lifespan, a popular health podcast that brings the cutting edge of aging and longevity science straight to you. Ground-breaking, Peabody Award-winning broadcast news journalist Carl Nelson, has interviewed Presidents, Prime Ministers, Heads of State, politicians, authors, celebrities, civic leaders, and people from all walks of life over a four-decade career that has taken him from Nelson Mandelas prison cell in South Africa to the Rodney King Riots in Los Angeles, to his present career as the host of Washington DCs latest daily newsmaker radio program weekdays from 6-10 am on WOL 1450am, WOLB Talk 2023 House / Tech / Progressive / Deep / Melodic / Techno / Edm / Afro / ibiza DJ Mix / Set / Podcast / Electronic Dance Music Radio Tomorrowland workout club 2022 party playlist beach tribal tiesto top best Defected 2021 Beats. Timestamps: They share the latest experimental and clinical data for NAD boosters, resveratrol, fisetin, quercetin, rapamycin, spermidine, metformin, and berberine. * Twitter This podcast is distinct from Dr. Sinclair's teaching and research roles at Harvard Medical School. (00:46:08) Physical Activity & Senescent Cells (00:41:48) Optimizing Exercise and Activity-mimetics * Levels - https://levels.link/sinclair Episode 5: Medical Interventions (TRT, HGH, Stem Cells, Peptides, etc.) (00:03:14) Goal of the Lifespan Podcast Too bad, that's your prejudice showing, you bigot. Professor Ampim will also contends Woodson was one of the first scholars to study the history of the African diaspora. $7 in honor of the 7 sirtuins, the signaling proteins involved in metabolic regulation and key players in longevity. They begin by highlighting how different types of physical activity (i.e., low-intensity aerobic exercise, high-intensity aerobic exercise, and weight training) protect against age-related disease and enhance longevity. * InsideTracker - https://insidetracker.com/sinclair They begin by highlighting how different types of physical activity (i.e., low-intensity aerobic exercise, high-intensity aerobic exercise, and weight training) protect against age-related disease and enhance longevity. Special thanks to our research assistants, Adiv Johnson & Sarah Ryan. Different interventions aimed at preserving brain health are also discussed, including a plant-based diet, exercise, metformin, NAD boosters, and sufficient sleep.Thank you to our sponsors: Athletic Greens - https://athleticgreens.com/sinclair Levels - https://levels.link/sinclair InsideTracker - https://insidetracker.com/sinclairOur Patreon page: https://www.patreon.com/davidsinclairLifespan book: https://amzn.to/3sUqurTDr. (00:36:57) Resveratrol, NAD Boosters, and Hyaluronic Acid Before Brother Peter, Journalist Simeon Booker Muhammad will discuss Malcolm's importance to o, My guest today is someone who has been leading a global health revolution around using food as medicine to support longevity, energy, mental clarity and happiness. (00:32:13) The Epigenome and Biological Age are Impacted by Exercise Special thanks to our research assistants, Adiv Johnson & Sarah Ryan. Biotracking, Age Reversal & Other Advanced Health Technologies | Episode 8. The information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. Still, her dad kept finding ways to, as she described, bribe her to share her voice and nurture her creative impulse, often in writing, from poems to stories and beyond. Chris Twitter: https://twitter.com/RealCSharp Chris Instagram: https://www.instagram.com/christopher Liberation Times Twitter: https://twitter.com/LiberationTimes Liberation Times Website: https://www.liberationtimes.com/ SUPPORT DISCLOSURE TEAM !, Paul Sinclair is recognised within the field of unexplained phenomena for his honest no nonsense approach to the subject. Thank you to our sponsors: In Episode 3 of the Lifespan Podcast, Dr. David Sinclair and Matthew LaPlante dive deeply into the science of non-dietary interventions that mimic adversity and promote health. Hosted by award-winning journalist Tim Samuels. * Twitter * InsideTracker - https://insidetracker.com/sinclair (00:58:02) Overall Message: Keep your Brain Healthy Hear about the latest developments in aging research, lifestyle practices for longevity, exercise and nutrition science, and more. Notes By MMiller. It could be that right now, the human race is having less sex than ever before. Dr Mark Hyman has been a practicing medical doctor for several decades, he is the Head of Strategy and Innovation at the Cleveland Clinic Center for Functional Medicine and the author of, Are you scrolling on your phone constantly? I aim to simplify it In this podcast, we hear stories from leading health experts and exciting personalities who offer easy health life-hacks, expert advice and debunk common health myths giving you the tools to revolutionise how you eat, sleep, move and relax. Lifespan with David Sinclair, Ph.D. (00:54:00) Information Theory of Aging The Lifespan with Dr. David Sinclair podcast, its employees, guests and affiliates assume no liability for the application of the information discussed. (00:00:00) Introduction The health entrepreneurship podcast focusing on big picture stuff. (00:21:26) Nicotinamide Mononucleotide * Levels - https://levels.link/sinclair (00:10:09) Human Growth Hormone I talked with Dr. Sinclair about his new study for this episode , Naturopathic Dr. Stephen Tates will explain how Sleep Deprivation can lead to dehydration, mood swings & other health issues. The information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. In this weeks episode, Dr. David Sinclair and co-host Matthew LaPlante zero in on drugs and supplements that have been reported to combat aspects of aging. Given the rise of dating apps, the sexual revolution and hormonal birth control, how is this happening? To stay up to date with David's work to democratize biological age testing and insights, visit tallyhealth.com. His book Lifespan: Why We Age and Why We Don't Have To is available now. The Lifespan with Dr. David Sinclair podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.Special thanks to our research assistants, Adiv Johnson & Sarah Ryan. Known mechanisms, limitations, and/or side effects associated with these molecules are additionally highlighted.Correction and clarification: At time point 1:07:37, Dr. Sinclair says he takes 1 gram of Spermidine, but the active ingredient in the capsules is 1-2 milligrams. * Facebook (00:51:27) Metformin Lifespan book: https://amzn.to/3sUqurT In a paper published last month, the Harvard biologist David Sinclair reports that he and his co-authors have found the answer. What does it mean to live a good life? For Longevity | Episode 5. Midland Cares mission: meeting individual needs through innovative care solutions. David Sinclair Social: Instagram Twitter FacebookMatthew LaPlante's Social: TwitterTo stay up to date with David's work to democratize biological age testing and insights, visit tallyhealth.com.Timestamps:(00:00:00) Launching Episode Six: Combating Cosmetic Aging & Improving Skin, Nails & Hair(00:02:54) Estrogen, Progesterone, and Menopause(00:09:51) Thanking the Sponsors(00:12:57) The Pinch Test, Epidermal Thinning, and Foot Ulcers(00:18:29) Skin and Biological Aging(00:23:19) Cellular Senescence, Ultraviolet Light, and Skin Aging(00:28:15) Collagen, Keratin, and Skin Health(00:33:38) A Quick Aside about Nails(00:34:45) Autophagy and Retinoids(00:36:57) Resveratrol, NAD Boosters, and Hyaluronic Acid(00:41:44) Botox, Skin Peels, and Microneedling(00:43:28) No Duh Stuff: Sun Damage, Smoking, Alcohol, and Bad Food(00:45:42) Hair Loss and Hair Graying(00:49:45) Topical Treatments, Pills, and Dihydrotestosterone(00:55:19) Frickin Laser Beams: Low-level Laser Therapy(00:57:59) Platelet-rich Plasma (PRP) Injections(01:00:11) Hair Aging, Stress, and Gray Hair Reversal(01:06:11) Targeting Aging Upstream(01:07:37) Todays Takeaways(01:09:25) Subscription and Support OptionsFor the full show notes, including the peer-reviewed studies, visit the Lifespan podcast website.Please note that Lifespan with Dr. David Sinclair is distinct from Dr. Sinclair's teaching and research roles at Harvard Medical School. (00:53:45) Repeatable Age Reversal and Safety Matthew LaPlante's Social: (01:08:27) Options for Subscription and Support (00:14:17) Cognitive Function and Plasticity For the full show notes, including the peer-reviewed studies, visit the Lifespan podcast website. (0:24:00) Evidence that Fasting can Attenuate Human Disease (1:06:44) Preview for Ep. (00:00:00) Launching Episode Six: Combating Cosmetic Aging & Improving Skin, Nails & Hair For the full show notes, including the peer-reviewed studies, visit the Lifespan podcast website. They share the latest research surrounding testosterone replacement therapy (TRT), human growth hormone (HGH), peptide supplementation, exosomes, stem cells, and cellular reprogramming. To start the program, Baltimore activists Kim Poole & Sister Swatara Olushola live in Rwanda. In this weeks exciting episode of the Lifespan podcast, Dr. David Sinclair and co-host Matthew LaPlante foray into potential anti-aging interventions that are truly on the cutting edge. #079 Blood-Brain Barrier Dysfunction in Alzheimers Disease and Dementia | Axel Montagne, Ph.D. Dr. David Horne & Finacial Expert Darnell Parker l The Carl Nelson Show, Dr. David Clark - Longdendale Lights & Earth Lights, #595 - 700k Q&A - Negative Self-Talk, Upcoming Live Tour & Ray Dalio, Microjoys: Finding Hope When Lifes Not Okay | Cyndie Spiegel, #594 - Dr Richard Wrangham - The Incredible Evolution Of Human Violence, Sadiki Bakari & Nuri Muhammad l The Carl Nelson Show, #339 BITESIZE | How to Live Your Best Life | Jake Humphrey, The Real Solution to Freeing Our Kids - and Ourselves - from Tech Addiction, with Gaia Bernstein. David Sinclair is a now professor in the Department of Genetics and co-director of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School. A professor in the Department of Genetics at Harvard Medical School and co-Director of the Paul F. Glenn Center for the Biological Mechanisms of Aging, David obtained his Ph.D. in Molecular Genetics . Matthew LaPlante's Social: Exercise, Heat, Cold & Other Stressors for Longevity | Episode 3. Thats one reason I felt like Gaia Bernsteins new book was talking directly to me. In this episode of the Lifespan podcast, Dr. David Sinclair and co-host Matthew LaPlante dissect the topic of brain aging. Please note that Lifespan with Dr. David Sinclair is distinct from Dr. Sinclair's teaching and research roles at Harvard Medical School. To stay up to date with David's work to democratize biological age testing and insights, visit tallyhealth.com. The Lifespan with Dr. David Sinclair podcast, its employees, guests and affiliates assume no liability for the application of the information discussed. Known mechanisms, limitations, and/or side effects associated with these molecules are additionally highlighted. (00:13:24) Survival Sensors (i.e., mTOR, AMPK, and Sirtuins) & Communicators (e.g., Insulin) (1:07:23) Subscription and Support For the full show notes, including the peer-reviewed studies, visit the Lifespan podcast website.